What magnesium to buy at the pharmacy. Magnesium B6 - what is it for and who will be harmful

Magnesium is an essential trace element that has been underestimated by society for a long time. The drug is important for the proper functioning of the nervous and muscular systems. It converts sugar into energy, maintains dental health, prevents calcium deposition and the formation of kidney stones, normalizes cardiovascular and endocrine functions, brain function, and facilitates the elimination of toxins and heavy metals. You can find a trace element in cereals, bread, tomatoes, liver, dairy products, eggs and fish.

The daily requirement of an adult is 400-500 mg of the substance, but the exact amount depends on the age, sex, height and weight of the person. Only a small percentage of people get the dose they need from food. In order to make up for the deficiency, it is recommended to take special substances.

Below are the TOP 10 best magnesium supplements based on user reviews and ratings, as well as expert recommendations. Attention, before using it, you must consult a doctor.

There are contraindications. Check with your doctor.

Top 10 best magnesium supplements

10 Evalar Magnesium B6

Affordable price
Country Russia
Average price: 312 rubles.
Rating (2019): 4.6

The drug is from a domestic manufacturer. The Evalar company is known to many for its large assortment of goods and good quality. Magnesium was no exception, which has earned recognition for its effectiveness and availability. The composition contains vitamin B6, which provides an additional effect on the immune system and its strengthening. The benefits become noticeable after 2-3 weeks, the course is designed for a month. Then, if necessary, you can repeat.

On the Internet, they write about such results as a reduction in impulsive actions, a decrease in the level of stress from a hectic pace of life in a noisy metropolis, a lesser effect of difficulties at work or in personal life on the emotional state. Suitable for use even for children due to the low content of the active ingredient. For some, this fact may be regarded as a disadvantage.

9 Pharmstandard Magnelis B6

Good composition
Country Russia
Average price: 444 rubles.
Rating (2019): 4.7

The product of the domestic company Pharmstandard is produced in combination with vitamin B6. Both are essential for maintaining health. Available in the form of tablets with a concentration of 50 mg. One package is enough for 2-3 weeks. The main advantage is the price, which is lower than similar ones on the market. However, since the supplement has a high consumption, in the calculations it turns out that with a long intake, the cost is average or even higher among similar products.

The action corresponds to the concentration of active elements. Users notice changes in state and improvement in sleep, but also note that when taking expensive analogues, the effect is more pronounced, since they have a higher percentage of the active substance. The remedy is best used for those who want to try magnesium and assess the need for taking for themselves. It is important to note that in the presence of diabetes mellitus, the drug is not recommended to be taken due to the glucose content.

8 21st Century Calcium, Magnesium, Zinc + D3

The best combination of price and quality
Country: USA
Average price: 450 rubles.
Rating (2019): 4.7

Magnesium from 21st Century is the most popular among the population, because it combines an attractive affordable price with good quality. Available in pill form. Additionally, the composition contains calcium, zinc and D3. It not only improves the nervous and muscular systems, but also supports immunity, good condition and appearance of teeth, hair, nails. In the production process, only natural products are used, gluten, starch, yeast and artificial preservatives are not used.

The manufacturer recommends taking 3 tablets a day for one month. During this time, the condition of the nails improves, the hair begins to fall out less and grow faster, and the susceptibility to stressful situations decreases. However, there are comments that the tool did not have the desired effect. One of the reasons is the presence of too many substances and their low concentration.

7 Life Extension Magnesium

Harmonious composition. Fast action
Country: USA
Average price: 790 rubles.
Rating (2019): 4.8

The essential mineral for health from the popular American manufacturer Life Extension is designed to normalize the emotional and physical condition of a person. It is completely safe to use, does not contain GMOs and is suitable even for vegetarians. The package contains 100 capsules with a dosage of 500 mg of the active substance. The cans are enough for 3-4 months of daily use.

The main advantage is a quick action and, due to this, a decrease in leg cramps, an improvement in mood, a decrease in the level of reactions to external stimuli and a comfortable digestion. Some shoppers report that perfect concentration "gives them peace and tranquility." A small disadvantage is such a side effect as diarrhea, but it does not appear in everyone and depends on the internal individual characteristics.

6 Nature "s Plus Animal Parade Mag Kidz Children" s Magnesium

The best drug for children
Country: USA
Average price: 685 rubles.
Rating (2019): 4.8

Taking magnesium is necessary not only for the proper functioning of the adult body, but also for the child too. The development of autism, dyslexia, attention deficit disorder, poor muscle development or hyperactivity can all arise from a lack of this element in a child. Nature's Plus Animal Parade helps solve this problem. The pleasant cherry flavor with no added sugar and the form of the animal tablets are very popular with children and are very happy to take it.

Numerous reviews point out that the result from the use is not long in coming. Anxiety, anxiety, mood swings and excessive emotionality in children are reduced. The child becomes more cheerful, more energetic, there is an appetite and interest in exploring new things. In the future, this helps in rapid growth, the formation of strong bones and skeleton. The only possible drawback is the release form, it can be difficult for very young children to chew tablets.

5 Sanofi Magne B6

Good quality. Convenient format
Country: France
Average price: 583 rub.
Rating (2019): 4.8

Sanofi is a French pharmaceutical company with the most leading position in the pharmaceutical market. Magnesium of the brand is loved for the ratio of high quality and convenient liquid release format. Due to the additional content of vitamin B6, human metabolism and digestion are accelerated. Thanks to the combination of ingredients and the correctly selected composition, the elements are quickly absorbed. An additional advantage is the availability of the product in all pharmacies in the country. This makes it possible to quickly purchase a product, and there is no need to place an order on the Internet, and then wait for delivery.

Reviews confirm the effectiveness, when taken, the deficiency of trace elements is replenished, symptoms of irritability, sleep disturbances, fatigue disappear, muscle spasms are reduced or completely disappear. At the same time, such drawbacks as rapid consumption and a strong overpricing relative to the amount of contents in a bottle are noted.

4 Now Foods Magnesium Citrate

High efficiency
Country: USA
Average price: 1,378 rubles.
Rating (2019): 4.9

Now Foods has been on the market since 1968. From the very beginning, the brand has been popular among millions due to its wide range of vitamins, as well as due to its effective effect when applied. All preparations are certified and comply with Russian and international quality standards. The brand's magnesium comes in a citrate format, which helps the body eliminate harmful substances faster and improve bowel function. The composition contains only herbal ingredients, there are no traces of gluten and milk. Due to this, it is suitable for use by vegetarians and people with intolerance to certain foods.

Numerous reviews speak of the invaluable benefits of the supplement for the nervous system. They note that it becomes easier to endure stressful situations, the general condition rises, drowsiness disappears and more strength and energy appears. The product is produced in the form of capsules, which are convenient for transportation. On average, a pack of 120 tablets is enough for 2 months of use.

3 Solgar Magnesium with Vitamin B6

The most popular brand. Fast effect
Country: USA
Average price: 1 380 rubles.
Rating (2019): 4.9

The company has been on the market for over half a century and produces various vitamins for human health. Magnesium Solgar is immensely popular for its superior quality at an affordable price. The composition contains vitamin B6, which provides support for energy metabolism and healthy functioning of the human nervous system. Suitable for vegetarians and people with allergies to food reagents, as it contains only natural ingredients without added GMOs. It is produced in the form of capsules, one package of 250 pieces is enough for 3-4 months.

The effect of taking is manifested immediately and persists for a long time after stopping the intake, since the drug accumulates in the body. Buyers note that when used, the ability to cope with stress and nervous situations increases. When playing sports, endurance increases, pains in bones and joints disappear.

2 Nature's Way Magnesium Complex

Natural composition
Country: USA
Average price: 2 024 rubles.
Rating (2019): 5.0

The most popular in terms of the number of reviews and ratings is magnesium from the American manufacturer Nature's Way. A large number of positive comments have been written about the supplement. Popularity is due to its natural composition, impressive result and quality. The product is suitable for daily use and does not contain allergens such as soy, gluten, milk and fish.

There is no vitamin B6 in the supplement, but many users advise purchasing and drinking them together for maximum results. However, even without supplements, when taken, the intestinal function is normalized, the emotional background is stabilized and problems with muscle pain are solved. It is important to note that the positive effect will not be noticeable immediately, but in a week, since the effect is cumulative and you will have to wait to fully appreciate it.

1 Doctor "s Best Magnesium

Better assimilation and quality. Allowed for pregnant women
Country: USA
Average price: 1,090 rubles.
Rating (2019): 5.0

The philosophy of the American company Doctor "s Best is" the best nutrition from a scientifically proven point of view ", they fully realize this through products. A distinctive feature of the brand's magnesium is the easiest absorption. The effect is achieved through the use of organic elements in the form of a chelate, which makes the drug completely tolerable for the stomach This is one of the few remedies on the market that has this property.

Content

The trace element magnesium is essential for the functioning of the entire body. It normalizes the functioning of the nervous and vascular-cardiac systems, improves sleep, digestion, and increases the body's energy. With its deficiency, hypomagnesemia and associated symptoms may develop. To compensate for the lack of an element, drugs with magnesium are prescribed.

Composition of preparations with magnesium

With hypovitaminosis, doctors prescribe magnesium preparations. There, the inorganic element is not contained in pure form, but in the form of salts or other compounds. It is forbidden to mix it with iron, because the absorption of both substances is reduced. Functions of magnesium salts and complexes:

The name of the substance that contains magnesium	Action on the body
	Soothing, analgesic, anticonvulsant, hypnotic, anti-stress, lowers blood glucose
	Relieves muscle pain, hypersensitivity in fibromyalgia
Asparaginate	Aminosuccinic acid salt improves metabolism, cardiac glycoside tolerance, exhibits antiarrhythmic action
Aspartate	Relieves fatigue, muscle hyperexcitability, has a high penetrating ability, participates in the production of cellular energy
	Spasmolytic, antiaggregatory, antiarrhythmic, participates in the formation of tricarboxylic acids
	Maintains ionic balance in the myocardium
	Laxative, restoring the function of the nervous system, eliminates lymphocytic leukemia
	Introduced intravenously, improves the functioning of the heart and blood vessels
Glycinate (gluconate)	Calming, relaxing, used to relieve chronic pain and muscle hypertonia
Salicylate (salitylate)	Eliminates pain, fever, relieves inflammation, normalizes collagenosis
	Easily absorbed, normalizes the state of the nervous system
	Regulates cell permeability, neuromuscular transmission, improves coronary circulation

Indications for use

Magnesium is considered very useful for the heart; it is taken to prevent vascular diseases. In the body, the element helps to break down glucose, carry out enzymatic reactions, increase the resistance of cells and promote their renewal. Magnesium in the presence of B vitamins increases the speed of neuromuscular transmission, relieves the manifestations of leg cramps.

Potassium, magnesium and calcium carbonate in a complex increase vascular tone, contract muscles, and activate the assimilation of each other. The optimal ratio of Mg and Ca 2: 1 - this preserves bone density, protects teeth from decay. Magnesium stabilizes cell membranes, accelerates the penetration of calcium, chlorine, potassium ions, lowers blood pressure and normalizes the rhythm of the heartbeat, the work of its valves. A person needs 300-400 mg of an element per day

Vitamins with magnesium and calcium

Preparations with magnesium and calcium are used for various conditions and diseases of the body. These include:

• hypertonicity of the uterus during pregnancy;
• hypertension or hypotension;
• arrhythmia;
• eclampsia and preeclampsia;
• nervous tic;
• edema of the walls of blood vessels;
• increased muscle tone, including leg cramps that occur at night;
• the need for a laxative effect or stimulation of the passage of bile.

Magnesium and vitamin B6 preparations

Magnesium preparations are especially popular for leg cramps. To stop them, vitamin B6 is added to the element, which enhances the effect of the substance and normalizes neuromuscular transmission. Pyridoxine hydrochloride additionally normalizes blood sugar levels, eliminates neurological disorders. Indications for the use of magnesium preparations with vitamin B6:

• cramps, tingling, feeling of "goose bumps" in the legs;
• other disorders of neuromuscular transmission;
• lack of B vitamins;
• dehydration, long-term treatment with diuretics or laxatives;
• electrolyte disturbances against the background of vomiting or diarrhea, frequent bowel cleansing with an enema, fasting, old age;
• numbness of the legs;
• diabetes;
• condition after resection of the small intestine;
• poisoning with aluminum, beryllium, lead, alcohol.

Taking medications with vitamin B6 and minerals during pregnancy is especially important. Means regulate the process of synthesis of nucleic acids, the transfer of genetic information from mother to fetus. The mineral relaxes the muscles of the uterus, intestines and other internal organs, which reduces the risk of miscarriage. The anti-stress effect of the element helps to normalize the sleep of a pregnant woman, reduce the hyperexcitability of the nervous system, and eliminate discomfort.

Vitamin B6 helps the body absorb magnesium. A woman taking drugs with these components in the early stages of pregnancy receives a high guarantee of the safe development of the fetus without complications. Minerals nourish the placenta, normalize blood pressure, prevent gestosis from developing, and reduce the risk of premature birth. Regular intake of magnesium products eliminates:

• nausea;
• spastic constipation;
• discomfort near the heart area;
• tearfulness, fatigue;
• aversion to odors.

Potassium and magnesium tablets

The combination of potassium and magnesium is the most common treatment for heart disease. Indications of their reception:

• compensation for potassium losses with prolonged use of non-potassium-saving diuretics;
• therapy for chronic heart failure;
• ventricular arrhythmias, atrial fibrillation, paroxysmal tachycardia;
• atrial rhythm disturbances;
• prevention of extrasystole, attacks of paroxysmal tachycardia;
• frequent attacks of angina pectoris;
• unstable arterial hypertension;
• improved absorption of cardiac glycosides.

How to take pills

Magnesium preparations for the heart are more often available in tablet format. They are taken orally after meals in a dosage determined individually for each person, but not more than 300 mg per day. About a day, an adult receives 3-6 tablets for 2-3 doses. The course of treatment lasts about a month, unless otherwise prescribed by the doctor. The dosage for children is determined by their age - up to a year they give a quarter of a tablet a day, for babies 1-3 years old - half a tablet.

Children 3-6 years old are given half the dose twice a day, 7-10 years old - half a piece three times a day. A child of 11-12 years old is given a whole tablet twice a day, 13-16 years old - one tablet twice a day. From the age of 16, adult dosages are prescribed. Doses are adjusted depending on the type of magnesium in the preparation, the individual characteristics of the patient, the presence or absence of allergies.

Indications for taking mineral-based tablets are cardiovascular diseases, convulsions, irritability, fatigue, and insomnia. Solutions with magnesium are injected intravenously, 2–4 ampoules of 5–10 ml are diluted with 5% glucose solution, dripped for half an hour. If necessary, the procedure is repeated after 4–6 hours. In total, therapy lasts five days.

Contraindications and side effects

Potassium and magnesium preparations for the heart have their own contraindications and side effects. It is forbidden to use funds in the presence of the following diseases:

• hypersensitivity to the components of the composition;
• acute or chronic renal failure;
• anuria, oliguria;
• hypocorticism;
• autism, dyslexia;
• galactosemia;
• combination with levodopa;
• decreased serum creatinine levels;
• hyperthyroidism;
• disorders of urination;
• psoriasis;
• diabetes;
• treatment with cytostatics;
• hypermagnesemia;
• cardiogenic shock;
• dehydration;
• hemolysis;
• acute metabolic acidosis;
• cardiogenic shock;
• atrioventricular block;
• severe myasthenia gravis;
• the risk of edema.

Drugs are prescribed with caution during pregnancy, breastfeeding, urolithiasis diathesis, hypophosphatemia, hyperkalemia. Against the background of the use of magnesium agents, side effects may develop. These include:

• disruption of the digestive system: nausea, diarrhea, vomiting, burning in the epigastrium, abdominal pain, dry mouth, discomfort, dyspepsia, gastric bleeding, ulceration of the gastrointestinal tract mucosa, impaired absorption in the large or small intestine;
• malfunctions of the heart: impaired myocardial conduction, decreased blood pressure, atrioventricular block, cardiovasculitis;
• dysfunction of the nervous system: convulsions, paresthesia (loss of sensitivity), hyporeflexia;
• hypersensitivity: itching, skin rash, redness, hyperemia, swelling, urticaria, anaphylactic shock;
• development of hypermagnesemia: feeling of heat, respiratory depression, drowsiness;
• convulsions, fever.

List of drugs with magnesium

Among the wide variety of drugs in pharmacies, you can choose products that are tested and approved by doctors. Popular mineral-based medicines:

Drug name	The form of the element in the composition of the tool	Amount of active component per piece	Package volume, pcs.	Approximate price for a pack in Moscow, rubles
	Lactate dihydrate
Magnelis B6
Magnesium B6
Magnerot	Orotata dihydrate
Doppelherz active magnesium + B vitamins
Magnesium compliant
Asparkam	Asparaginate		20 tablets
Panangin	Asparaginate		60 tablets
Magnesium Chelate NSP			60 tablets
			250 tablets

P N013203 / 01, P N013203 / 02.

Trade name of the drug:

Magne B 6 ®.

Dosage form:

film-coated tablets, oral solution.

Composition

Film-coated tablets

Tablet core:
active ingredients:
magnesium lactate dihydrate * - 470 mg;
pyridoxine hydrochloride - 5 mg;
excipients: sucrose - 115.6 mg, heavy kaolin - 40.0 mg, acacia gum - 20.0 mg, carboxypolymethylene 934 - 10.0 mg, talc (magnesium hydrosilicate) - 42.7 mg, magnesium stearate - 6.7 mg.
Tablet shell: acacia gum - 3.615 mg, sucrose - 214.969 mg, titanium dioxide - 1.416 mg, talc (magnesium hydrosilicate) - traces, carnauba wax (powder) - traces.
* - equivalent to the content of magnesium (Mg ++) 48 mg

Oral solution
Active ingredients:
magnesium lactate dihydrate ** - 186 mg;
magnesium pidolate ** - 936 mg;
pyridoxine hydrochloride - 10 mg;
excipients: sodium disulfite - 15 mg, sodium saccharinate - 15 mg, cherry-caramel flavor - 0.3 ml, purified water up to 10 ml.
** - equivalent to the total content of magnesium (Mg ++) 100 mg

Description
oval biconvex tablets, coated white, with a smooth shiny surface.
Oral solution: transparent brown liquid with a caramel smell.

Pharmacotherapeutic group

Magnesium drug.

ATX code: A11JB.

Pharmacological properties

Pharmacodynamics

Magnesium is a vital element that is found in all tissues of the body and is necessary for the normal functioning of cells, participates in most metabolic reactions. In particular, it is involved in the regulation of the transmission of nerve impulses and in muscle contraction. The body gets magnesium from food. Lack of magnesium in the body can be observed in violation of the diet (diet) or with an increase in the need for magnesium (with increased physical and mental stress, stress, pregnancy, use of diuretics). Pyridoxine (vitamin B 6) is involved in many metabolic processes, in the regulation of the metabolism of the nervous system. Vitamin B 6 improves the absorption of magnesium from the gastrointestinal tract and its penetration into cells.
Serum magnesium content:

from 12 to 17 mg / l (0.5 - 0.7 mmol / l) indicates a moderate magnesium deficiency;

below 12 mg / L (0.5 mmol / L) indicates severe magnesium deficiency. Pharmacokinetics
Absorption of magnesium in the gastrointestinal tract is no more than 50% of the oral dose. 99% of the magnesium in the body is found inside cells. Approximately 2/3 of intracellular magnesium is distributed in bone tissue, and the other 1/3 is in smooth and striated muscle tissue. Magnesium is excreted mainly in the urine. At least 1/3 of the dose of magnesium is excreted in the urine.

Indications for use

Established magnesium deficiency, isolated or associated with other deficiency conditions, accompanied by symptoms such as: increased irritability, minor sleep disturbances; gastrointestinal cramps or heart palpitations; increased fatigue, pain and muscle spasms, tingling sensation.

Contraindications

Hypersensitivity to drug components.

Severe renal failure (creatinine clearance less than 30 ml / minute).

Phenylketonuria.

Children under 6 years of age (for the drug in the form of tablets) and up to 1 year (for solution).

Fructose intolerance, glucose-galactose malabsorption syndrome, sucrase-isomaltase deficiency (only for the drug in the form of tablets due to the presence of sucrose in the composition).

Simultaneous administration of levodopa (see section "Interaction with other medicinal products").

Carefully
With a moderate degree of renal failure, since there is a risk of developing hypermagnesemia.

Application during pregnancy and lactation

Pregnancy

Clinical experience of using the drug in a sufficient number of pregnant women did not reveal any adverse effect on the occurrence of fetal malformations or fetotoxic effects.
Magne B 6 ® can be used during pregnancy only if necessary, on the advice of a doctor.
Breastfeeding period

Magnesium passes into breast milk. Avoid using the drug during lactation and breastfeeding.

Method of administration and dosage

Before taking the drug, you should consult your doctor.
Film-coated tablets

Adults are advised to take 3-4 ampoules per day.
For children over 1 year old (body weight over 10 kg), the daily dose is 10-30 mg magnesium / kg body weight (0.4-1.2 mmol magnesium / kg) or 1-4 ampoules.
The daily dose should be divided into 2-3 doses, taken with meals.
The tablets should be taken with a glass of water.
The solution from the ampoules is dissolved in? glasses of water.
Treatment should be discontinued immediately after the normalization of the concentration of magnesium in the blood.

Attention
Self-breaking ampoules with Magne B 6 ® do not require a file. To open the ampoule, take it by the tip, having previously covered it with a piece of cloth, and break it off with a sharp movement, first from one pointed end, and then from the other, after directing the first open end of the ampoule at an angle into a glass of water, so that the second the tip of the ampoule was not over the glass. After breaking off the second tip of the ampoule, its contents will freely pour into the glass.

Side effect

Immune system disorders

Rarely (< 0,01%): аллергические реакции, включая кожные реакции.
Gastrointestinal disorders

Unknown frequency (according to the available data, it is not possible to estimate the frequency of occurrence): diarrhea, abdominal pain, nausea, vomiting, flatulence.

Overdose

Symptoms

With normal kidney function, an overdose of magnesium when taken by mouth usually does not lead to toxic reactions. However, in the case of renal failure, magnesium poisoning may develop.
Overdose symptoms, the severity of which depends on the concentration of magnesium in the blood: lowering blood pressure; nausea, vomiting; oppression of the central nervous system, decreased reflexes; changes in the electrocardiogram; respiratory depression, coma, cardiac arrest and respiratory paralysis; anuric syndrome.
Treatment

Rehydration, forced diuresis. Renal failure requires hemodialysis or peritoneal dialysis.

Interaction with other medicinal products

Contraindicated combinations

With levodopa: the activity of levodopa is inhibited by pyridoxine (if taking this drug is not combined with taking inhibitors of peripheral decarboxylase of aromatic L-amino acids). Any amount of pyridoxine should be avoided unless levodopa is taken in combination with aromatic L-amino acid peripheral decarboxylase inhibitors. Combinations not recommended

The simultaneous use of drugs containing phosphates or calcium salts can impair the absorption of magnesium in the intestine.
Combinations to be taken into account

When prescribing tetracyclines by mouth, it is necessary to observe an interval of at least three hours between the ingestion of tetracycline and Magne B 6 ®, since magnesium preparations reduce the absorption of tetracyclines.

special instructions

Information for patients with diabetes mellitus: coated tablets contain sucrose as an excipient.
In the case of severe magnesium deficiency or malabsorption syndrome, treatment begins with intravenous administration of magnesium preparations.
In the event of a concomitant calcium deficiency, it is recommended that the magnesium deficiency be corrected before taking calcium supplements or calcium supplements.
With frequent use of laxatives, alcohol, strenuous physical and mental stress, the need for magnesium increases, which can lead to the development of magnesium deficiency in the body.
The ampoules contain sulfite, which can cause or intensify the manifestations of allergic-type reactions, including anaphylactic reactions, especially in patients at risk.
When pyridoxine is used in high doses (more than 200 mg per day) for a long time (over several months or in some cases, years), sensory axonal neuropathy may develop, which is accompanied by symptoms such as numbness, impaired proprioceptive sensitivity, and distal tremor limbs and gradually developing sensory ataxia (impaired coordination of movements). These abnormalities are usually reversible and resolve when vitamin B 6 is stopped.
The tablet formulation is intended only for adults and children over 6 years of age. For young children (over 1 year old), the drug is recommended in the form of an oral solution.Impact on the ability to drive vehicles and engage in other potentially hazardous activities
Does not affect. There are no specific recommendations.

Release form

Film-coated tablets
10 tablets in a PVC / aluminum foil blister. 5 blisters, together with instructions for use, are placed in a cardboard box.
Oral solution
10 ml of the drug in dark glass ampoules (hydrolytic class III EF), sealed on both sides, with a break line and two marking rings on each side. 10 ampoules in a cardboard packing insert together with instructions for use are placed in a cardboard box.

Shelf life

Film-coated tablets: 2 years.
Oral solution: 3 years.
The drug should not be used after the expiration date.

Storage conditions

Film-coated tablets: in a dry, dark place at a temperature not exceeding 25 ° C.
Oral solution: in a dark place at a temperature not exceeding 25? С.
Keep out of the reach of children.

Vacation conditions

Available without a prescription.

Manufacturer

Film-coated tablets
Sanofi Winthrop Industry. 82, Avenue Raspail, 94250 Gentilly - France.
Oral solution Sanofi Winthrop Industry. 82, Avenue Raspail, 94250 Gentilly, France. Cooperation Pharmaceutical Francaise. Place Lucien Over 77020 Melan, France. Consumer claims should be sent to:
125009, Moscow, st. Tverskaya, 22.

The required daily intake of magnesium for women is about 350 milligrams, and for men - 450 milligrams. Many products contain this trace element, but there is difficulty with the possibility of its correct and complete assimilation in the body. That is why it becomes impossible to get the full daily dose of magnesium on a daily basis from food alone.

In this case, magnesium in tablets comes to the rescue, which is presented in pharmacy chains in a wide variety of drugs. The trace element is considered one of the most important from the periodic table, which is necessary for every cell in the body. Its main effect occurs on nerve impulses occurring in the brain and peripheral nerve endings.

With a sufficient amount of Mg in the body, the absorption of calcium in tablets or from foods is much better, which is vital for maintaining healthy and strong nails, bones and hair. A high demand for Mg can be observed with high activity associated with the physical and mental nature of the activity, as well as with numerous stresses and during pregnancy.

Important! The main function of magnesium is to provide energy for the body from the outside in order to effectively break down glucose. A high content of the trace element is observed in cereals, cabbage, most nuts, legumes, seafood and fish of marine origin. The easiest absorption of Mg can be achieved through the consumption of dairy products such as cottage cheese or milk.

The preservation of bone tissue and dental skeleton is excellently achieved by using a certain ratio of calcium and magnesium with food or preparations - two to one. These two microelements complement each other and stabilize cell membranes. Thanks to the synthesis of B vitamins, magnesium is able to improve nerve and muscle transmission in the body.

According to world medical statistics, more than 50 percent of people suffer from magnesium deficiency to varying degrees, which adversely affects the physical and emotional state of the body. In order to find out the content of a particular trace element, you can contact a specialist who will prescribe the correct diagnosis and blood test.

Choosing a drug can seem daunting for someone who is not familiar with modern pharmacy. In pharmacies, a huge variety of tablets are presented, each of which differ in the form of release, the final content of magnesium in percent or mg, as well as the combination with other drugs. When choosing a remedy, you need to pay attention to the composition, indications and contraindications of each remedy.

Principles and features of the use of magnesium tablets

Magnesium tablets have main indications for use, among which the following can be distinguished:

1. The very first indication is a deficiency of this trace element in the human body.
2. The occurrence of arrhythmia, angina pectoris and atherosclerosis, which is associated with a lack of magnesium.
3. Heart failure, which is a chronic disease.
4. Disruption of metabolic processes in fat cells.
5. Frequent spasmodic reactions in blood vessels and muscles.
6. Magnesium tablets for the heart help improve heart function and restore the usual rhythm.
7. Pain in the muscles.
8. Increased fatigue, frequent stressful conditions and sleep disturbances.

Features of the use of magnesium tablets are in their combined use not only with calcium, but also with vitamins of group B 6. They will strengthen each other and lead to the most positive effect on the body. Bioavailability and better absorption of the trace element is achieved by adding pyridoxine to it. Together with vitamin B 6, the element will be better absorbed and retained inside the cells.

It is most profitable in terms of efficiency and price to purchase products with a combined composition, in which all trace elements and vitamins will complement each other. You can start taking any drug only with a doctor's prescription. The usual dosage of one tablet contains 50 milligrams of magnesium, so 5 to 7 tablets should be taken by mouth per day.

Before you start self-treatment with pills, you need to find out all their contraindications for use, among which are:

• stones in the bladder and urinary tract;
• renal failure;
• violation of the body's ability to absorb glucose;
• cirrhosis of the liver;
• ascites;
• intolerance to milk sugar;
• children under eighteen years of age

Effervescent tablets are convenient to use, which are prescribed by course methods. The duration of one course of treatment is from four to six weeks, after which it is recommended to take a break of several months in order not to get an excess of the trace element in the body.

Among the side effects of magnesium preparations are allergic reactions, impaired and upset appetite, nausea and diarrhea. In addition, tablets are not recommended to be used without the supervision of specialists during pregnancy and lactation, since a person is not able to independently regulate the level of balance of an element in the blood.

Say a word about great magnesium

Magnesium is an essential macronutrient in the body and ranks fourth after sodium, potassium and calcium in its prevalence in the human body. Perhaps for this he got his name, which means "great" from Latin. He is called " controller general"Because it controls almost every chemical reaction in the body, participates in many processes: in the synthesis of proteins, fats, carbohydrates, the metabolism of about 300 enzymes, energy production, glucose uptake, nerve signal transmission, building bone tissue, regulation of vascular relaxation and tension, and muscles. It has a calming effect, reducing the excitability of the nervous system and enhancing the processes of inhibition in the cerebral cortex, acts as an anti-allergic and anti-inflammatory factor, protects the body from infection by participating in the production of antibodies, plays a significant role in the processes of blood clotting, regulation of the intestines, bladder and prostate gland.

According to some reports, in industrialized countries about 50% of the population is magnesium deficient... With a lack of magnesium, the entire body suffers, you can make a huge list of disorders and complications.

To increase the level of magnesium in the body, doctors and nutritionists recommend using drugs and supplements with magnesium in a bioavailable form. Before taking the drug, even prescribed by a doctor, it is advisable to familiarize yourself with the indications, contraindications and study the features of taking the drug.

The main indications for the appointment of magnesium:

Identified magnesium deficiency, isolated or associated with other deficiency conditions, accompanied by symptoms such as:

Increased irritability.

Minor sleep disturbances.

Gastrointestinal cramps.

Heart palpitations.

Increased fatigue.

Pain and muscle spasms.

Tingling sensation in the muscles.

True, these symptoms can be caused by other reasons, but if they are eliminated by an additional intake of magnesium, then the reason for their appearance is in it. In any case, the drug cannot be taken without a doctor's prescription, who will tell you the dosage and course of treatment.

P it is important to familiarize yourself with the contraindications before taking:

Hypersensitivity to any component of the drug.

Severe renal or adrenal insufficiency (creatinine clearance less than 30 ml / min).

Phenylketonuria.

Age up to 6 years (efficacy and safety have not been established).

Hereditary galactosemia, glucose and galactose malabsorption syndrome or lactase deficiency (due to the presence of lactose in the preparation).

Simultaneous administration of levodopa.

Features of reception

1) Taking magnesium supplements is recommended in conjunction with taking vitamin B6 - these substances enhance each other's action. In addition, pyridoxine (vitamin B6) improves the bioavailability of magnesium: magnesium forms complexes with the vitamin, which are absorbed better than magnesium itself. Vitamin B6 promotes the penetration of magnesium into cells and its storage inside them, enhances most of the pharmacological effects of magnesium.

Therefore, if you are taking calcium or iron supplements, then 2-3 hours should pass between taking these drugs and magnesium so that they do not interfere with each other's absorption. The same applies to the combination with sodium fluoride preparations and tetracyclines.

3) It is undesirable to take magnesium between meals, as it can cause abdominal pain and even lead to diarrhea.

The use of magnesium and B6 during pregnancy

During pregnancy, I first encountered the need to take magnesium and B6 preparations, when

my doctor prescribed magne

B6 forte. As usual, I first studied this drug, and then bought ... but only a cheaper analogue on iherb (more on that below) and I know for sure that this is not a fake, unlike purchases in our pharmacies, where, at times, there are a lot counterfeit products.

So why prescribe a combination of magnesium + B6 during pregnancy?

The fact is that during pregnancy in women, the need for magnesium increases 2-3 times, which is necessary for both the mother's body and the baby. The daily diet does not always include the required amount of magnesium. According to research results, more than 80% (data from MAGIC 1 for 2012 and MAGIC 2 for 2013) of pregnant women in Russia suffer from magnesium deficiency. Therefore, doctors often prescribe magnesium-containing preparations during this period.

Magnesium preparations during pregnancy are prescribed only by a doctor. Sometimes you can find instructions for the mandatory delivery of an analysis to determine the content of magnesium in the blood serum. However, given the fact that when magnesium deficiency occurs, it can be released from the bones, preventing a decrease in its serum concentration, then such an analysis may not show the real "picture". Actually, my doctor did not prescribe any tests, the lack of magnesium was, as they say, on the face.

The most common symptoms of a magnesium deficiency are:

• Muscle spasms, tics, cramps, uterine hypertonicity;


• Headaches, dizziness, sleep disturbances, decreased performance, increased anxiety, irritability;


• Hypertension, hypotension, arrhythmia, heart pain and heart palpitations;


• Unstable stools, vomiting, nausea;


• Lowered body temperature, chilliness, a tendency to edema.

What is the benefit of taking magnesium preparations for a pregnant woman and a child?

• reduces at times the threat of termination of pregnancy associated with hypertonicity of the uterus. After all, magnesium has a tocolytic effect - it relaxes the muscles of the uterus, relieves spasms and helps to put the nervous system in order. Its ions keep the entire muscular system in a calm state and quickly suppress increased muscle excitability;


• prevents complications associated with premature placental abruption, maintains the function of the placenta;


• maintains balance in the blood coagulation system, strengthens connective tissues, participates in the control of blood pressure;


• supports full growth and development of the fetus, because necessary for protein synthesis and tissue building, contributes to the normal development of the child's nervous system;


• helps in the treatment of preeclampsia and eclampsia, a severe pathology of pregnancy, which is fatal to mother and child.

A lack of magnesium can lead to various problems, for example, to the formation of malformations of the mitral valve of the heart, joints, etc. in a child. There is evidence that deficiency can potentiate the development of autism, dyslexia, attention deficit disorder, hyperactivity in children. In the literature, you can find many other "horror stories", but it is better to consult a doctor if you notice manifestations of magnesium deficiency in yourself than to read, and even worse - to clear up the consequences of Mg + deficiency later.

Selection of magnesium preparations

There are quite a lot of drugs containing magnesium in pharmaceuticals today. They differ in the form of release, the amount of "elementary" magnesium, bioavailability and combination with other elements, more often with vitamin B6 for the reasons described above.

The amount of "elemental" magnesium (pure magnesium) in the preparation depends on which chemical compound the manufacturer used as a source of magnesium. For example, the amount of magnesium:

Magnesium gluconate contains 5.8%, i.e. 100 mg of magnesium gluconate contains only 5.8 mg of magnesium itself,

In magnesium chloride -12%,

In magnesium citrate - 16.2%,

In glycinate - 50%

In magnesium oxide - the maximum amount of magnesium is 60.3%.

Thus, when choosing a drug with magnesium, it is advisable to compare not the amount of magnesium compound, but the content of pure magnesium. Unfortunately, manufacturers do not always indicate this.

Absorption rate - The bioavailability of magnesium compounds also varies.
Inorganic magnesium compounds: oxide, hydroxide, sulfate, chloride.

Organic magnesium compounds: pidolate, citrate, lactate, gluconate, aspartate, ascorbinate, salicylate, glycinate and orotate.

There is a widespread opinion that organic magnesium compounds are better absorbed from the gastrointestinal tract than inorganic ones, however, the results of the studies conducted do not always confirm this point of view, and the confirming, sometimes, are not entirely correct.

If you dive deeply into the study of the forms of magnesium, then you can find sources that distinguish magnesium lactate as the best in terms of assimilation, others - citrate, others - glycinate, so there is no consensus here. Magnesium carbonate and sulfate are the worst absorbed, this information is often repeated in different sources, so it is better not to pay attention to these forms.

I opted for a preparation with magnesium oxide and vitamin B6 (manufactured by Solgar) because this form contains the largest amount of pure magnesium (and this means the minimum amount of unnecessary impurities) and it has a decent bioavailability (this is evidenced by significant improvements in laboratory parameters with its use).

The problem of choice is not only a question of the composition of the drug, but also its price, comparing the Russian assortment with analogues of foreign online pharmacies and stores, so now I offer you my small review.

Overview of magnesium preparations in Russian and American stores